Department Of Medical Laboratory Science Journals


ABSTARCT

All procedures in the diagnostic medical laboratories are not without associated risks. Laboratory personnel handling clinical samples containing highly infectious agents are at a high risk of contracting laboratory-acquired infection. This risk is particularly high for those working in microbiological laboratories [1,2]. Injuries through infected needles and sharp cutting instruments encounteredin diagnostic procedures represent potential sources of laboratory-acquired infections.


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ABSTARCT

Low birth weight (LBW) remains a global health challenge with both short and long term adverse consequences1. It is an important indicator of the health status of an infant and a principal factor that determines the infant survival, physical and mental development in the future2. Its etiology is complex and may vary from one setting to another. Delivery of LBW neonates has been associated with pre- term deliveries, anaemia, malnutrition and poor use of orthodox ante-natal services1,3,4.These are particularly…
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Background:

Ergonomics awareness helps in its right application and contributes significantly to general wellbeing and safety of worker at workplace. Aim: This cross?sectional descriptivestudy aimed at assessing the level of awareness and knowledge of the science of ergonomics mong Medical Laboratory Scientists in Benin City, Nigeria. Subjects and Methods: A totalof 106 medical laboratory scientists comprising 64 and 42 in public and private laboratories, respectively, were recruited for this study using systematic random sampling technique. Data were obtained…
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ABSTARCT

Sexually transmitted infections (STIs) including HIV/AIDS are global health concerns. Sexually transmitted infections are high among young people in Africa, largely due to high risk behaviour and neglect of potential preventive measures. Particularly distressing is the fact that nearly 3.3 million youth are living with HIV/AIDS in sub Saharan Africa, and 76% of these youth are women(1). In sub Saharan Africa young women within the age group of 15-24 years are 3-4 times more likely to be infected with…
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ABSTARCT

Hepatiatis B and C viral infections are global health problems.Data on the prevalence of these viruses among preganat women in rural Nigeria is missing. This study was carried out with a view to determine the prevalence of Hepatitis B and C Virus infections in pregnant women in Okada Community of Edo State,Nigeria and assess risk factors for their transmission. Venous blood was collected from two hundred and sixty seven (267) pregnant women with age ranging from 13-42 years. A…
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ABSTARCT

The human immunodeficiency virus (HIV) is a teething global health problem. Sub?Saharan Africa remains by far the most affected region, with 24.5 million people living with HIV, representing a little below two?thirds of all people living with HIV.[1] HIV epidemic affects females severely in the sub?region, and women of reproductive age make up 57% of adults living with HIV.[1] HIV infection in pregnancy is associated with adverse maternal and fetal outcome,[2] the effect of which includes among others infectious…
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ABSTRACT

Tuberculosis (TB) and HIV/AIDS are two worldwide public health concerns.[1] Co-infection of these two diseases has been considered to be a major obstacle for the global efforts in reaching the goals for the prevention of HIV and TB infections.[1] HIV infection is a risk factor predisposing to Mycobacterium tuberculosis infection and progression to active disease.[2] Findings from some studies indicate that peopleliving with HIV have a higher risk of developing multi-drug resistant tuberculosis (MDR-TB) which is associated with increased…
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Malaria is the world's leading parasitic disease and affects approximately 40% of the world's population (ap-proximately 2.4 billion people) in more than 100 countries (1). A life threatening illness arising from malaria infection, usually referred to as severe malaria, may occur in 1 – 2 % of infection (2, 3). Of the five clinically relevant Plasmodium species (Plasmodium falciparum, P. vivax, P. ovale, and P. malariae, P. knowlesi), P. falciparum mainly accounts for severe malaria, an important cause…
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ABSTARCT

Intestinal parasitic infections are associated with morbidity and mortality worldwide. Data on prevalence of intestinal parasitic infection is sparse in rural Nigeria. Against this background, this study aimed at determining the prevalence of intestinal parasitic infections within a four year period in the rural community of Okada, Edo State, Nigeria. Fecal samples obtained from 1528 patients (consisting of 740 males and 788 females) presenting with signs and symptoms of gastroenteritis at the Igbinedion University Teaching Hospital, Okada were examined…
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Abstract
Objectives: To determine the prevalence of malaria and anemia among pregnant women attending a traditional birth center as well as the effect of herbal remedies, gravidity, age, educational background and malaria prevention methods on their prevalence. Methods: Blood specimens were collected from 119 pregnant women attending a Traditional Birth Home in Benin City, Nigeria. Malaria parasitemia was diagnosed by microscopy while anemia was defined as hemoglobin concentration Results: The prevalence of malaria infection was (OR=4.35 95% CI=1.213, 15.600; p=0.016) higher among primigravidae (92.1%). Pregnant women (38.5%)…
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Abstract
Aim: To determine the prevalence of urinary tract infection (UTI) in Okada, a rural community in Nigeria, and the effect
of age and gender on its prevalence as well as the etiologic agents and the susceptibility profile of the bacterial agents. Patients and Method: Clean-catch midstream urine was collected from 514 patients (49 males and 465 females). The urine samples were processed and microbial isolates identified. Susceptibility testing was performed on all bacterial isolates. Result: The prevalence of urinary tract…
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METHODS: Clean-catch urine was collected from 220 pregnant women attending a traditional birth home in Benin City, Nigeria. Urine samples were processed, and microbial isolates identified using standard bacteriological procedures. A cross-sectional study design was used.

CONCLUSIONS: The prevalence of urinary tract infection among pregnant women was 55.0% and significantly affected by gestational age and parity. The most prevalent etiologic agent observed was Escherichia coli. With the exception of the flouroquinolones, aminoglycoside, and Amoxicillin-cluvanate, the activity…
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Abstract
Background: Wound infections are associated with increased morbidity and mortality. Objectives: To determine the prevalence, aetiology and susceptibility profile of bacterial agents of wound infection among in- and- out patients at a rural tertiary hospital in Nigeria, within a 5 year period. Methods: Wound swabs collected from 156 out-patients and 353 in-patients were, cultured and microbial isolates identified using standard methods. Antibiotic susceptibility testing was done on bacterial isolates. Results: The prevalence of wound infection in 2006, 2007, 2008, 2009 and 2010 was 71.4%,…
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ABSTRACT
Molecular typing techniques have been employed in the epidemiological study of methicillin-resistant S. aureus (MRSA) and methicillin-resistant coagulase-negative staphylococci (MRCoNS) to identify the staphylococcal cassette chromosome mec (SCCmec) elements. The aim of this study was to determine the prevalence and diversity of SCCmec types in the isolates obtained from four hospitals in south-south, Nigeria. A total of 149 staphylococcal isolates were obtained from clinical samples from March through September, 2015. They were identified and SCCmec typing was done using single-target PCR. The prevalence of methicillin-resistant staphylococci…
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Sub- Saharan Africa remains by far the most affected region with about 24.5 million people living with HIV, representing a little below two-thirds of all people living with HIV in the world(Oladeinde et al., 2011 )

HIV infection is a major health concern in Nigeria, where it is estimated that about 2.9 million people are living with the virus (Monjok et al., 2009 ).


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Study Background: Moringa oleifera, (miracle tree), has been used in the treatment of numerous diseases. Moringa has been
the subject of intensive scientific research; however, there have been scanty information
on its sub-acute effect on the kidneys.
Aims: This work was done to investigate the histological and biochemical effect of M. oleifera on the heart
and kidneys of adult Wistar rats.
Settings and Design: Twenty-eight adult healthy rats were used for this study. The rats were divided into
4 groups…
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Abstract
is a proinflammatory cytokine which acts to worsen disease while IL-10 is an anti-inflammatory
cytokine, which acts to improve healing. Plasmodium falciparum co-infection with Mycobacterium tuberculosis
could generate both innate and acquired immunity involving inflammatory responses. This work was
designed to determine plasma level of TNF-Alpha and IL-10 in plasmodium co-infection with
Mycobacterium tuberculosis. The test subjects recruited for this study were M. tuberculosis mono-infected
patients (30), Plasmodium falciparum mono-infected patients (50) and M. tuberculosis and plasmodium coinfected
patients…
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ABSTRACT
Lassa fever caused by lassa virus is anhaemorragic infectious disease with limited access to
diagnostic facilities in Nigeria. Lassa virus infections can only be diagnosed definitively in the
laboratory using the following tests: reverse transcriptase polymerase chain reaction (RT-PCR) assaygold
standard, antibody enzyme-linked immunosorbent assay (ELISA), antigen detection tests and
virus isolation by cell culture. Cases of this infectious disease have been reported in 24 of the 36
States in Nigeria. Currently, two national laboratories are supporting the laboratory…
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Background:
Objectives
Method:
Results:
Conclusion:
Synergistic association between Human Immunodeficiency virus (HIV) and
pulmonary tuberculosis (PTB) infection has resulted in variable haematological manifestations
including coagulopathies; these accelerated the morbidity and mortality burden of HIV/PTB coinfection.
: Based on this preposition, we prospectively evaluated some coagulation biomarkers
in a case-controlled study of 102 HIV sero-positive subjects consistent withWHOclinical stages I
and II, 56 HIV/PTB co-infected subjects; both groups were therapy naive. Also 104 HIV seronegative
healthy blood donorswere recruited as control…
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Abstract: Hepatitis B and C viruses cause viral hepatitis which could affect the function of the liver. Viral hepatitis is
one of the major killer diseases associated with malaise but could be prevented. This work was designed to investigate
the frequency of HBsAg, and anti-HCV including their effects on some biochemical parameters among University
Students presenting with malaise. Fifty malaise University students were recruited through their Health Centre. The
students were screened for anti-HCV, anti-HIV and HBsAg Immunochemical by ELIZA…
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Abstract Anthropometric indices and lipid profiles are useful markers of malnutrition and could reveal risk of cardiovascular disease. This work aimed at evaluating the anthropometric indices and lipid profiles in students of tertiary institutions. Anthropometric indices and lipid profiles were evaluated in 200 students of students of tertiary institutions including Achievers University and Rufus Giwa Polytechnic, Owo, Nigeria, aged 18 -46 years, comprising 95 males and 105 females recruited for this study. Anthropometric measurements including weight, height, and waist and…
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Abstract Background: Anthropometric indices, plasma albumin, uric acid and packed Cell Volume(PCV) are good markers of malnutrition and the associated disorders. Aim and Objective: This work aimed to evaluate the anthropometric indices, plasma albumin, uric acid and packed cell volume in tertiary institution students. Materials and Methods : Anthropometric indices, plasma albumin, uric acid and packed cell volume (PCV) were evaluated in 200 students of two tertiary institutions in Owo-Nigeria which include Achievers University and Rufus Giwa polytechnic, Owo, Ondo…
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ABSTRACT
Background: Solanecio biafrae (Wòròwó) contains phytochemicals, specifically antioxidants such as vitamins with effective health benefits as it is evidenced in the use of the vegetable in traditional treatments. Acetaminophen is an anagelsic which people used irrationally that could lead to drug abuse and inflammation of the liver in overdoses or prolong administration, notwithstanding the normal therapeutic dose is safe. Materials and Methods: Fifteen rabbits of the same sex (male) with weight ranging from 1.0 -1.4 Kg were classified into…
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ABSTRACT
Background: Watermelon juice has many non- scientific health beneficial claims due to its bioactive chemical constituents. Acetaminophen Extra contains paracetamol (500mg) and caffeine(65mg) used to relieve pain. Aim and Objective: This work was designed to evaluate the effect of watermelon juice in rabbits overdosed with acetaminophen extra using plasma zinc, potassium, chloride and sodium. Materials and Method: Thirty rabbits classified into six experimental groups labeled A-F (with C1, C2, E1 and E2) with A as control were investigated. An…
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Abstract: Water melon juice contain potent antioxidants such as lycopene in addition to other health promoting bioactive
phytochemicals. Overdoses of the analgesic and antipyretic acetaminophen extra represent one of the most common
pharmaceutical product poisonings worldwide today. This work was designed to evaluate the effect of watermelon juice
in rabbits overdosed with acetaminophen extra using Total cholesterol, Triglyceride, HDL and LDL. Thirty rabbits
classified into 6 groups labeled A-F (with C1, C2, E1 and E2) with A as control were…
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Abstract: Obesity is the result of interplay between genetic and environmental factors. Polymorphisms in various genes
controlling appetite and metabolism predispose to obesity when sufficient calories are present. It is not known whether
polymorphisms in FXR gene are associated with high lipid level among obese individuals. This study was designed to
investigate and compare the lipid profile and polymorphism of the FXR gene in obese individuals, overweight and
normal weight individuals. We investigated 35 obese subjects, 35 overweight subjects and…
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Abstract
Thirty anaemic pregnant women aged 29.5± 6.5 years with baseline mean packed cell volume (PCV) of 20.8 ± 2.0% were studied. Freshly prepared Ugu (pumpkin-Telfaira occidentalis) mixture containing ugu (pumpkin) fluid, raw content of egg and peak evaporated unsweetened milk was administered orally to each of the pregnant women three times in a day for seven days. Packed cell volume was carried out by capillary tube method. There was an observed significantly mean value of PCV (29.5 ± 2.2%…
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